British Journal of Haematology: Vol 191, No 5

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British Journal of Haematology

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British Journal of Haematology: Volume 191, Issue 5

Issue Information

Issue Information

Images in Haematology

Oropharyngeal psychogenic purpura

Severe airport malaria complicated by macrophage activation syndrome

Commentary

Preventing transfusion-associated graft-versus-host disease with blood component irradiation: indispensable guidance for a deadly disorder

BSH guidelines for the use of irradiated blood components: guidance that is needed

Direct-acting antiviral agents in lymphoproliferative disorders: more complex than expected

Autologous stem cell transplant in first remission for transformed indolent non-Hodgkin lymphoma: additional data to guide practice

The evolution of clinical research in thalassaemia: where has all the funding gone?

Investigating the missing heritability of fetal haemoglobin level in Africa

Long-term cognitive impairments following recovery in the patients with immune-mediated thrombotic thrombocytopenic purpura

Reviews

Antibody-based immunotherapy for treatment of immunoglobulin light-chain amyloidosis

How we treat older patients with acute myeloid leukaemia

The role of high-dose melphalan with autologous stem-cell transplant in multiple myeloma: is it time for a paradigm shift?

Guidelines

Guidelines on the use of irradiated blood components

British Society for Haematology Guidelines on transfusion for fetuses, neonates and older children (Br J Haematol. 2016;175:784–828). Addendum August 2020

British Society of Haematology Guidelines on the spectrum of fresh frozen plasma and cryoprecipitate products: their handling and use in various patient groups in the absence of major bleeding (Br J Haematol. 2018;181:54–67). Addendum August 2020

Guideline for diagnosis and management of hairy cell leukaemia (HCL) and hairy cell variant (HCL-V)

Haematological Malignancy – Clinical

The simplified follicular lymphoma PRIMA-prognostic index is useful in patients with first-line chemo-free rituximab-based therapy

Anticoagulation prophylaxis reduces venous thromboembolism rate in adult acute lymphoblastic leukaemia treated with asparaginase-based therapy

Genomic analysis of multiple myeloma using targeted capture sequencing in the Japanese cohort

Real-world non-interventional long-term post-authorisation safety study of ruxolitinib in myelofibrosis

Direct-acting antiviral agents for hepatitis C virus-mixed cryoglobulinaemia: dissociated virological and haematological responses

Haematological Malignancy – Biology

Lenalidomide and pomalidomide potently interfere with induction of myeloid-derived suppressor cells in multiple myeloma

p53 is associated with high-risk and pinpoints TP53 missense mutations in mantle cell lymphoma

Transplantation

Autologous stem cell transplantation for untreated transformed indolent B-cell lymphoma in first remission: an international, multi-centre propensity-score-matched study

Paediatric

Benefits of risk-adapted and mould-specific antifungal prophylaxis in childhood leukaemia

Long-term follow-up of children with risk organ-negative Langerhans cell histiocytosis after 2-chlorodeoxyadenosine treatment

Prevalence of germline GATA2 and SAMD9/9L variants in paediatric haematological disorders with monosomy 7

Short reports

Adjuvant tyrosine kinase inhibitor therapy improves outcome for children and adolescents with acute lymphoblastic leukaemia who have an ABL-class fusion

Platelets, Thrombisis and Haemostasis

Role of bone marrow-derived mesenchymal stem cell defects in CD8+CD28– suppressor T-lymphocyte induction in patients with immune thrombocytopenia and associated mechanisms

Characteristics and outcomes of adults with cytomegalovirus-associated thrombocytopenia: a case series and literature review

Cerebral MRI findings predict the risk of cognitive impairment in thrombotic thrombocytopenic purpura

Haemoglobinopathies

Cumulative outcome of pre-implantation genetic diagnosis for sickle cell disease: a 5-year review

Hydroxycarbamide exposure and ovarian reserve in women with sickle cell disease in the Multicenter Study of Hydroxycarbamide

F cell numbers are associated with an X-linked genetic polymorphism and correlate with haematological parameters in patients with sickle cell disease

Co-morbidities and mortality associated with transfusion-dependent beta-thalassaemia in patients in England: a 10-year retrospective cohort analysis

Red cells and Iron

All-trans-retinoic acid shifts Th1 towards Th2 cell differentiation by targeting NFAT1 signalling to ameliorate immune-mediated aplastic anaemia

Transfusion

The Kg-antigen, RhAG with a Lys164Gln mutation, gives rise to haemolytic disease of the newborn

Correspondence

A real-world study of panobinostat, weekly bortezomib and dexamethasone in a very heavily pretreated population of multiple-myeloma patients

Loss-of-function mutations in CSF3R cause moderate neutropenia with fully mature neutrophils: two novel pedigrees

Rapid fluorescence in situ hybridisation optimises induction therapy for acute myeloid leukaemia

Clinical features of vitamin B12 deficiency mimicking thrombotic microangiopathy

Body weight is negatively associated with direct oral anticoagulant trough concentrations in dabigatran and apixaban users

Online only

Paraneoplastic acute demyelinating disease with monoclonal gammopathy of unknown significance expressing aquaporin-4

A high TP53 mutation burden is a strong predictor of primary refractory mantle cell lymphoma

Reporting of race and ethnicity at an international haematology conference

Indomethacin is an effective treatment in adults and children with bone Langerhans cell histiocytosis (LCH)

Dynamic evolution of ponatinib-resistant mutations in BCR–ABL1-positive leukaemias revealed by next-generation sequencing

High infiltration of CD20+ B lymphocytes in extranodal natural killer/T-cell lymphoma is associated with better prognosis

Venetoclax plus hypomethylating agent in blast-phase myeloproliferative neoplasm: preliminary experience with 12 patients

A Sardinian founder mutation in glycoprotein Ib platelet subunit beta (GP1BB) that impacts thrombocytopenia

Microcytosis in patients with haemoglobin C trait: is α-thalassaemia trait to blame?

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Related Title

Role of bone marrow-derived mesenchymal stem cell defects in CD8⁺CD28^– suppressor T-lymphocyte induction in patients with immune thrombocytopenia and associated mechanisms

High infiltration of CD20⁺ B lymphocytes in extranodal natural killer/T-cell lymphoma is associated with better prognosis